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The receptor then desensitizes rapidly and enters in a very transient inactive state, characterized because of the existence of bound agonist (By similarity). While in the existence of CACNG4 or CACNG7 or CACNG8, reveals resensitization which is characterized by a delayed accumulation of present-day flux upon continued application of L-glutamate (By similarity). As a result of intricate development with NSG1, GRIP1 and STX12 controls the intracellular destiny of AMPAR and also the endosomal sorting with the GRIA2 subunit towards recycling and membrane concentrating on (By similarity)
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